Clark School Home UMD

ISR News Story

Kanold group research published in PNAS

ISR-affiliated Assistant Professor Patrick Kanold (Biology) and his colleagues have just had their mammalian-brain research, “Electrical synapses formed by connexin36 regulate inhibition- and experience-dependent plasticity” published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS).

The research shows that elimination of electrical synapses formed by connexin36 altered inhibitory efficacy and caused frequency facilitation of inhibition consistent with a decreased GABA release in the inhibitory network. The altered inhibitory efficacy was paralleled by a failure of theta-burst long-term potentiation induction and by impaired ocular dominance plasticity in the visual cortex. Together, these data suggest a unique mechanism for regulating plasticity in the visual cortex involving synchronization of inhibitory networks via electrical synapses.

Related Articles:
Kanold study shows autism may begin early in brain development
UMD neuroscience researchers publish in the journal Neuron
Yin, Fritz, Shamma publish neuroplasticity study in Journal of Neuroscience
Kanold study in Neuron: A short stay in darkness may heal hearing woes
Researchers part of two NSF Neural & Cognitive Systems grants worth more than $1.2 million
BBI FY17 Seed Grant Winners Announced
Fritz, Shamma are collaborators on new DARPA Targeted Neuroplasticity Training Program
NSF Science Now video features 'aging brain' research of Anderson, Simon and Presacco
It’s not your ears, it’s your brain
BBI Seed Grant winners announced

August 16, 2011


Prev   Next

 

 

Current Headlines

Gabriel gives keynote address at First International Conference on the Economics of Natural Gas

Sarah Bergbreiter wins ISR Outstanding Faculty Award

Ayan Mallik wins ISR Graduate Student Award

Three ISR graduate students win new travel award

Alexis Jenkins wins ISR staff award

UMD Opens Outdoor Flight Laboratory to Advance Autonomy, Robotics

Salamanca-Riba Appointed 2017/2018 UMD ADVANCE Professor 

Raghavan writes article on teaching for OR/MS Today magazine

Clark School names Hamid Jafarkhani 2017 IHOF Inductee

Relive Totality With Clark School Images, Videos

News Resources

Return to Newsroom

Search News

Archived News

Events Resources

Events Calendar