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Fabrication and Integration of Polymeric BioMEMS (ISR IP)

ISR intellectual property available to license

Reza Ghodssi, Gary Rubloff, Mark Kastantin, Sheng Li, Li-Qun Wu, Hyunmin Yi, Jung Jin Park

U.S. Patent: 7,375,404

A variety of methods are used to fabricate microfluidic devices. Channels can be micromachined into silicon using traditional microelectronic techniques. However, glass and silicon processing are time consuming and expensive often require the use of hazardous materials.

The present invention provides a micro-electro-mechanical device having a substrate, a patterned microchannel on the substrate and an encapsulation membrane covering the microchannel. The encapsulation membrane is reversibly attachable and separable relative to the patterned structure.

The device is constructed using biomolecular engineering and nano-biotechnology biofabrication through the use of materials such as Chitosan (a bio compatible natural polymer), and by processes employing Tyrosinase-catalyzed Macromolecular Assembly, and Transglutaminase-catalyzed Macromolecular Assembly.

For more information
If you would like to license this intellectual property, have questions, would like to contact the inventors, or need more information, contact ISR External Relations Director Jeff Coriale at or 301.405.6604.

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You can go to our main IP search page to search by research category or faculty name. Or view the entire list of available IP on our complete IP listing page.

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Programmable Selective Deposition of Biofunctional Polymer Surfaces (ISR IP)
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June 21, 2007

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For more information, contact ISR External Relations Director
Jeff Coriale at or 301.405.6604.

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