Clark School Home UMD

ISR News Story

Kanold group research published in PNAS

ISR-affiliated Assistant Professor Patrick Kanold (Biology) and his colleagues have just had their mammalian-brain research, “Electrical synapses formed by connexin36 regulate inhibition- and experience-dependent plasticity” published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS).

The research shows that elimination of electrical synapses formed by connexin36 altered inhibitory efficacy and caused frequency facilitation of inhibition consistent with a decreased GABA release in the inhibitory network. The altered inhibitory efficacy was paralleled by a failure of theta-burst long-term potentiation induction and by impaired ocular dominance plasticity in the visual cortex. Together, these data suggest a unique mechanism for regulating plasticity in the visual cortex involving synchronization of inhibitory networks via electrical synapses.

Related Articles:
UMD researchers find listening to sound changes how neurons interact within the brain
Kanold study shows autism may begin early in brain development
UMD neuroscience researchers publish in the journal Neuron
Yin, Fritz, Shamma publish neuroplasticity study in Journal of Neuroscience
Kanold study in Neuron: A short stay in darkness may heal hearing woes
Maryland researchers develop computational approach to understanding brain dynamics
Maryland researchers awarded $1M DARPA Lagrange program cooperative agreement
Improving speech intelligibility testing with new EEG methods
Researchers part of two NSF Neural & Cognitive Systems grants worth more than $1.2 million
BBI FY17 Seed Grant Winners Announced

August 16, 2011


Prev   Next

 

 

Current Headlines

Khaligh, McCluskey to lead new $2.37M DOE solar power converter project

Nau, Gelfand, Goldstein part of MURI developing the potential of mean-field game theory

ECE Names 2017-2018 Distinguished Dissertation Fellows

UMD Celebrates Invention of Year Winners, Ventures, and Partnerships at 'Innovate Maryland'

Ulukus named Anthony Ephremides Professor in Information Sciences and Systems

Maryland researchers develop computational approach to understanding brain dynamics

Alumnus Raef Bassily joins Ohio State as tenure-track faculty

Maryland researchers awarded $1M DARPA Lagrange program cooperative agreement

Bill Regli featured at Global Industrial Cooperation Conference

Brin Family Prize to Support Excellence in Drone-Related Activity

News Resources

Return to Newsroom

Search News

Archived News

Events Resources

Events Calendar