The medial and lateral superior olives (MSO and LSO) are the two nuclei most intimately involved in binaural processing. The MSO effectively cross-correlates the signals arriving at the two ears [.Colburn Popper 1996.], thus computing interaural-time-delays due to sound location along the azimuth. The coincidence detector cells involved in this process have unique anatomical and physiological properties [.Carr Amagai 1996.]. LSO cells, in contrast, are sensitive to interaural intensity differences also due to sound source location. In this project we propose to develop detailed compartmental and computational models of these cells [.Carr Amagai 1996, Carr 1993, Han Colburn 1993, Agmon-Snir 1996, Diranieh Colburn 1994.], that are coupled to the physiological, developmental, and anatomical studies underway in our laboratories [.Rigby Carr 1996, Popper Colburn 1996.]. These modeling studies will serve as a bridge between the physiology ( Thrust area I) and the psychophysics of binaural processing ( Thrust area III) and will play an important role in our proposed work on multisensor fusion ( Thrust areas I and II).